Reducing Molecular Shuttling to a Single Dimension

2000 ◽  
Vol 112 (2) ◽  
pp. 358-361 ◽  
Author(s):  
David A. Leigh ◽  
Alessandro Troisi ◽  
Francesco Zerbetto
Keyword(s):  
2012 ◽  
Vol 111 (1) ◽  
pp. 266-268 ◽  
Author(s):  
Xiao Zhang ◽  
Xue Ke ◽  
Xiaoyan Wang

The Parent Form of the Social Competence Scale (SCS–PF) was translated into Chinese and validated in a sample of Chinese preschool children ( N = 443). Results confirmed a single dimension and high internal consistency in the SCS–PF. Mothers' ratings on the SCS–PF correlated moderately with teachers' ratings on the Teacher Form of the Social Competence Scale and weakly with teachers' ratings on the Student–Teacher Relationship Scale.


Entropy ◽  
2021 ◽  
Vol 23 (5) ◽  
pp. 498
Author(s):  
Chen Zhang ◽  
Kevin Welsher

In this work, we present a 3D single-particle tracking system that can apply tailored sampling patterns to selectively extract photons that yield the most information for particle localization. We demonstrate that off-center sampling at locations predicted by Fisher information utilizes photons most efficiently. When performing localization in a single dimension, optimized off-center sampling patterns gave doubled precision compared to uniform sampling. A ~20% increase in precision compared to uniform sampling can be achieved when a similar off-center pattern is used in 3D localization. Here, we systematically investigated the photon efficiency of different emission patterns in a diffraction-limited system and achieved higher precision than uniform sampling. The ability to maximize information from the limited number of photons demonstrated here is critical for particle tracking applications in biological samples, where photons may be limited.


1995 ◽  
Vol 38 (3) ◽  
pp. 714-725 ◽  
Author(s):  
Jill E. Preminger ◽  
Dianne J. Van Tasell

The purpose of the present research was to examine the relation between speech quality and speech intelligibility. Speech quality measurements were made using continuous discourse and a category rating procedure for the following dimensions: intelligibility, pleasantness, loudness, effort, and total impression. Measurements were made using a group of listeners with normal hearing for a set of stimulus conditions in which intelligibility varied, and for a set of stimulus conditions in which intelligibility was held constant near 100%. When ratings were made for a set of stimulus conditions in which intelligibility was allowed to vary (a) intersubject reliability was high (i.e., different listeners interpreted the dimensions in a similar manner); and (b) the speech quality dimensions of intelligibility, effort, and loudness were indistinguishable. When ratings were made for a set of stimulus conditions in which intelligibility was held constant (a) intersubject reliability was reduced, indicating that different listeners interpreted the dimensions in different ways; (b) most listeners rated each dimension differently, indicating that the dimensions were unique; and (c) across listeners, no single dimension was highly correlated with total impression. These results can be used in order to examine the relation between speech quality and speech intelligibility.


2020 ◽  
Author(s):  
William Jimenez-Leal ◽  
Samuel Murray ◽  
Santiago Amaya ◽  
Sergio Barbosa

We argue that people regularly encounter situations characterized by the presence of moral conflicts among permissible options. These scenarios, which some have called morally charged situations, reflect perceived tensions between moral expectations and moral rights. Studying responses to such situations marks a departure from the common emphasis on sacrificial dilemmas and widespread use of single-dimension measures. In 6 experiments (n=1607), we show that people use a wide conceptual arsenal when assessing actions that can be described as suberogatory (bad but permissible) or supererogatory (good but not required). In Experiment 1 we find that people freely describe actions as suberogatory or supererogatory. Experiment 2 shows that they differentially assess these actions in terms of how permissible, optional, and good they considered them. Experiment 3 tests the use of these evaluative dimensions with sacrificial dilemmas. We found that differences between these categories did not emerge when people respond to dilemmas, even when controlling for trait utilitarian tendencies. By including judgments of blameworthiness and sanction, Experiments 4 and 5 provided additional evidence of the richness sub/super erogatory evaluations. In Experiment 6 people offered their own explanations of their responses. Qualitative analyses revealed that they frequently appeal to character traits, the presence of rights, and the absence of explicit duties. Taken together these results suggest a richer spectrum of both situations and concepts relevant to characterize moral judgment than moral psychologists up to this point have generally recognized. (First three authors contributed equally)


2018 ◽  
Author(s):  
William H.B. McAuliffe ◽  
Michael E. McCullough ◽  
Debra Lieberman

Although the possibility sounds paradoxical, several studies have found that positive and negative regard for others’ welfare are orthogonal and have unique personality correlates. We tested whether this result is an artefact of treating the oft-used self-report altruism scale (SRA) as unidimensional. In a pilot study of students and community-dwelling adults (N = 276, 190 women; Meanage = 21.67, SDage = 7.49), we factor analyzed the SRA. We confirmed its factor structure in a study of Mechanical Turk workers (N = 814; 410 women; Meanage = 36.6, SDage = 11.19). Using an S-1 bifactor model, we created a “gold standard” general altruism factor composed of idiographic, behavioral, and questionnaire measures. We used structural equation modeling to assess how the SRA and the gold standard measure relate to gender, sexual history, and malevolence. The SRA contained three factors across both studies. The factor that accounted for the most variance positively correlated with sadism and psychopathy, a history of uncommitted sex, and being male. The other two SRA factors and the gold standard measure generally evinced the opposite associations. In conclusion, regard for other’s welfare is likely a single dimension of personality with a unified nomological network.


2013 ◽  
Vol 66 (2) ◽  
pp. 299-318 ◽  
Author(s):  
Andy J. Wills ◽  
Fraser Milton ◽  
Christopher A. Longmore ◽  
Sarah Hester ◽  
Jo Robinson

1977 ◽  
Vol 29 (1) ◽  
pp. 107-116 ◽  
Author(s):  
John Long

Detection and recognition studies are reviewed, which show a dependency between errors on successive trials. They suggest the impairment accompanying the presentation of simultaneous signals may also involve a similar “between-trial” component. The hypothesis was tested using a two-choice recognition paradigm with bimodal signals. Dimensions presented simultaneously were interleaved on alternate trials with a single dimension presented alone. Interleaving two signals in the first experiment showed no effect on the following signal presented alone, compared to a control condition in which the signal always preceded itself. Interleaving four signals in the second experiment produced a significant impairment. Accounts of the results based on the length of the response interval, fluctuations of state variables such as arousal and decay of the memory trace are rejected. Accounts based on the impairment and set-size of preceding simultaneous signals are retained. Both suppose part of the impairment accompanying simultaneous signals to be a between-trial phenomenon. Implications of the results for work on divided-attention are considered and a method of experimental control proposed.


Author(s):  
Jean-Loup Seban

Emil Brunner was one of the most influential Protestant theologians of the twentieth century. He was a minister of the Swiss Reformed Church, a professor at the University of Zurich, and held distinguished lectureships in England, the USA and Japan. He joined the ‘dialectical school’ early in his career, but tried to rehabilitate natural theology, which led to a rift with Barth. His works were widely read and often served as basic texts in Reformed and Presbyterian seminaries. He rejected the historicist reduction of Christ to a wise teacher figure that was characteristic of neo-Protestantism. He was also critical of modern philosophical anthropologies – as propounded by Marx or Nietzsche, for example – because he felt that they reduced human essence to a single dimension. Only theological anthropology can fully interpret human essence; and of central importance here is the ‘I–Thou encounter’, whereby the fulfilment of the human ‘I’ is achieved through a relationship with the divine ‘Thou’. Brunner also unfolded an original view on the relation of theology to philosophy. Reason, he argued, is essential for the elucidation and communication of faith. Philosophy, in so far as it indicates the limitations of reason, can serve to prepare us for the revelation of the Absolute.


2019 ◽  
pp. 256-299
Author(s):  
Neil Brenner

The question of uneven spatial development has long been a central concern for critical sociospatial theorists. But how, precisely, is the spatiality of this process to be conceptualized? Drawing on Henri Lefebvre’s striking metaphor of social space as a mille-feuille—a flaky French pastry composed of “a thousand layers”—this chapter argues that the geographies of uneven development are best conceived as a polymorphic superimposition and interpenetration of sociospatial relations. Alongside its scalar dimensions, uneven spatial development is also mediated through the dynamics of territorialization, place-making, and networking. The morphologies of sociospatial relations under capitalism are too intricately interwoven to be reduced to a single dimension, scalar or otherwise. This chapter thus offers a series of autocritical reflections on the scalar analytics elaborated in the preceding chapters while also outlining several major challenges for future research on the variegated spatialities of capitalist urbanization.


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